Genetic Clustering of Tuberculosis in an Indigenous Community of Brazil.

Genetic Clustering of Tuberculosis in an Indigenous Community of Brazil.

We conducted a population-based study of tuberculosis (TB) from 2009 to 2015 in an indigenous community of Brazil, the largest in the country, to investigate risk factors associated with recent TB transmission. The clinical isolates of Mycobacterium tuberculosis were genotyped by IS6110-RFLP (restriction fragment length polymorphism) and spoligotyping analysis. Among 67 isolates typed by RFLP, …

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Combining Bayesian genetic clustering and ecological niche modeling: Insights into wolf intraspecific genetic structure.

Combining Bayesian genetic clustering and ecological niche modeling: Insights into wolf intraspecific genetic structure.

The distribution of intraspecific genetic variation and the way it pertains to environmental components is of accelerating curiosity to researchers in macroecology and biogeography. Recent research investigated the relationships between the setting and patterns of intraspecific genetic variation throughout species ranges however solely few rigorously examined the relation between genetic teams and their ecological niches. …

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Clusterin in Alzheimer's Disease: Mechanisms, Genetics, and Lessons From Other Pathologies.

Clusterin in Alzheimer’s Disease: Mechanisms, Genetics, and Lessons From Other Pathologies.

Clusterin (CLU) or APOJ is a multifunctional glycoprotein that has been implicated in a number of physiological and pathological states, together with Alzheimer’s illness (AD). With a outstanding extracellular chaperone perform, extra roles have been mentioned for clusterin, together with lipid transport and immune modulation, and it’s concerned in pathways frequent to a number of …

Clusterin in Alzheimer’s Disease: Mechanisms, Genetics, and Lessons From Other Pathologies. Read More »

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