Bridging-induced microphase separation: photobleaching experiments, chromatin domains and the need for active reactions.

We review the mechanism and consequences of the ‘bridging-induced attraction’, a generic biophysical principle that underpins some existing models for chromosome organization in 3D.

This attraction, which was revealed in polymer physics-inspired computer simulations, is a generic clustering tendency arising in multivalent chromatin-binding proteins, and it provides an explanation for the biogenesis of nuclear bodies and transcription factories via microphase separation.

Palladium Standard, 100UL

C016-100UL 100UL
EUR 123

Glutathione Standard, 100UL

C018-100UL 100UL
EUR 122

Histone H3 Polyclonal Antibody, Rabbit, 100UL

A004-100UL 100UL
EUR 263

MonoMe Lys4 Histone H3 Polyclonal, Rabbit, 100UL

A005-100UL 100UL
EUR 263

DiMe Lys4 Histone H3 Polyclonal, Rabbit, 100UL

A006-100UL 100UL
EUR 263

TriMe Lys4 Histone H3 Polyclonal, Rabbit, 100UL

A007-100UL 100UL
EUR 263

Neptune 100ul barrier tip

BT100 10 trays of 96 / pack
EUR 59
Description: Low retention, Racked, Pre-Sterile, Sample Saving Surface

100UL ZYMARK TIPS, RACKED

ZT-100-R 960/pk
EUR 208
Description: Robotic Tips; Robotic tips - Axygen

10-100UL SINGLE CHANNEL PIPETTOR

AP-100 1/pk
EUR 182
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

100UL UNIVERSAL FIT FILTER TIPS

TF-100 1000/pk
EUR 418
Description: Filter Tip; Filter Tips Pipette - Axygen

100UL "MAXYMUM RECOVERY" FILTER TIPS

TF-100-L 1000/pk
EUR 456
Description: Filter Tip; Maximum Recovery Filter Tips - Axygen

Amikacin Sulfate USP (1:2)

A003-1G 1 g
EUR 92

Amikacin Sulfate USP (1:2)

A003-5G 5 g
EUR 239

6-TAMRA, SE in DMSO:100uL

90097 100uL
EUR 307
Description: Minimum order quantity: 1 unit of 100uL

6-Rox, SE in DMSO:(100uL)

90098 100uL
EUR 307
Description: Minimum order quantity: 1 unit of 100uL

100UL MAXYMUM RECOVERY ZYMARK TIPS, RACKED

ZT-100-L-R 960/pk
EUR 245
Description: Robotic Tips; Maxymum Recovery Robotic Tips - Axygen

100UL ZYMARK TIPS, RACKED & PRE-STERILIZED

ZT-100-R-S 960/pk
EUR 227
Description: Robotic Tips; Robotic tips - Axygen

10-100ul Filter Tip, Natural, 1000/Pack

FT224 1PK, 1000UNIT
EUR 79.58
  • Product category: Labware/Pipette Tips - Filter Tips/10-100ul

100UL ZYMARK FILTER TIPS, RACKED & PRE-STERILIZED

ZTF-100-R-S 960/pk
EUR 433
Description: Robotic Tips; Filter Tips Robotic Tips - Axygen

AXYPET 10-100UL SINGLE CHANNEL PIPETTOR ISO17025 3X4

AP-100-ALT 1/pk
EUR 199
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET 10-100UL SINGLE CHANNEL PIPETTOR ISO17025 3X10

AP-100-STD 1/pk
EUR 203
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

10-100ul Filter Tip, Natural, Sterile, 96/Rack

FT224-RNS 1PK, 96UNIT
EUR 53.92
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TF-100-L-R-S 960/pk
EUR 301
Description: Filter Tip; Maximum Recovery Filter Tips - Axygen

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TF-100-R-S 960/pk
EUR 258
Description: Filter Tip; Filter Tips Pipette - Axygen

LAMBDA PLUS SINGLE CHANNEL PIPETTOR,10 TO 100UL,AUTOCLAVABLE

4073 1/pk
EUR 182
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Single Channel Pipettors

100UL MAXYMUM RECOVERY ZYMARK FILTER TIPS, RACKED & PRE-STERILIZED

ZTF-100-L-R-S 960/pk
EUR 478
Description: Robotic Tips; Max Rec Robotic Filter Tips - Axygen

10-100ul Filter Tip, Natural, Sterile, 96/Rack x 10

FT224-RNSB 1PK, 960UNIT
EUR 98.74
  • Product category: Labware/Pipette Tips - Filter Tips/10-100ul

100UL CLEAR PIPET TIPS FOR "OASIS" AUTOMATED LIQUID HANDLING SYSTEM

OT-100-R 960/pk
EUR 362
Description: Robotic Tips; Robotic tips - Axygen

LAMBDA PLUS SINGLE CHANNEL PIPETTOR,10 TO 100UL,AUTOCLAVABLE ISO17025 3X4

4073-ALT 1/pk
EUR 199
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Multi-Channel Pipettors

LAMBDA PLUS SINGLE CHANNEL PIPETTOR,10 TO 100UL,AUTOCLAVABLE ISO17025 3X10

4073-STD 1/pk
EUR 203
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Single Channel Pipettors

100UL AXYGEN MULTIRACK FILTERED TIP, RACKED, STERILE, 960/PCK 5 PCK/CASE

MRF-100-R-S 960/pk
EUR 327
Description: Filter Tip; MultiRack Filter tips

100UL CLEAR PIPET TIPS FOR TECAN EVO/ CALIPER ZEPHYR AUTOMATED LIQUID HANDLING SYSTEM

EV-100-R 960/pk
EUR 348
Description: Robotic Tips; Robotic tips - Axygen

TIPS, 100UL NAT GRAD LOW BIND BARRIER IN HINGED RACKS,S,BK,960/3840

4137 960/pk
EUR 341
Description: Filter Tip; Deckwork Filter Tips

100UL AXYGEN MULTIRACK FILTERED TIP, RACKED, STERILE, MAXYMUM RECOVERY, 960/PCK 5 PCK/CASE

MRF-100-L-R-S 960/pk
EUR 357
Description: Filter Tip; MultiRack Maxymum Recovery Filter tips

100UL CLEAR PRE-STERILIZED FILTERED PIPET TIPS FOR TECAN EVO/ CALIPER ZEPHYR AUTOMATED LIQUID HANDLING SYSTEM

EVF-100-R-S 960/pk
EUR 403
Description: Robotic Tips; Filter Tips Robotic Tips - Axygen

Eukaryotic Translation Initiation Factor 1 (EIF1) Antibody

abx330291-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

F-Box And Leucine Rich Repeat Protein 4 (FBXL4) Antibody

abx330292-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

CG8889-RA Antibody

abx330293-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ERBB3) Antibody

abx330294-100ul 100 ul
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Proto-oncogene c-Rel (REL) Antibody

abx330295-100ul 100 ul
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Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) Antibody

abx330296-100ul 100 ul
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  • Shipped within 5-10 working days.

ATP Binding Cassette Transporter A13 (ABCA13) Antibody

abx330297-100ul 100 ul
EUR 425
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Alpha 2B Adrenergic Receptor (ADRA2B) Antibody

abx330298-100ul 100 ul
EUR 425
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Aldo-Keto Reductase Family 1 Member C8, Pseudogene (AKR1C8P) Antibody

abx330299-100ul 100 ul
EUR 425
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abx330301-100ul 100 ul
EUR 425
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CKLF Like MARVEL Transmembrane Domain Containing Protein 1 (CMTM1) Antibody

abx330302-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

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abx330303-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

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EUR 425
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EUR 425
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EUR 425
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Sodium Voltage-Gated Channel Alpha Subunit 7 (SCN7A) Antibody

abx330309-100ul 100 ul
EUR 425
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Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14) Antibody

abx330310-100ul 100 ul
EUR 425
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Zinc Finger With KRAB And SCAN Domains 5 (ZKSCAN5) Antibody

abx330311-100ul 100 ul
EUR 425
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Diacylglycerol Kinase Kappa (DGKK) Antibody

abx330312-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Antigen KI-67 (MKI67) Antibody

abx330313-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

ALK Receptor Tyrosine Kinase (ALK) Antibody

abx330314-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Arylsulfatase D (ARSD) Antibody

abx330315-100ul 100 ul
EUR 425
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ATP5G3 Antibody

abx330316-100ul 100 ul
EUR 425
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Cadherin EGF LAG Seven Pass G-Type Receptor 3 (CELSR3) Antibody

abx330317-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Collagen Type IX Alpha 3 (COL9A3) Antibody

abx330318-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Collagen Type V Alpha 2 (COL5A2) Antibody

abx330319-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Collagen Type V Alpha 3 Chain (COL5A3) Antibody

abx330320-100ul 100 ul
EUR 425
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abx330321-100ul 100 ul
EUR 425
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abx330322-100ul 100 ul
EUR 425
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Retinol Binding Protein 5, Cellular (RBP5) Antibody

abx330323-100ul 100 ul
EUR 425
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Cystatin 1 (CST1) Antibody

abx330324-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Fibroblast Growth Factor 18 (FGF18) Antibody

abx330325-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Glucosaminyl (N-Acetyl) Transferase 3, Mucin Type (GCNT3) Antibody

abx330326-100ul 100 ul
EUR 425
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KN Motif And Ankyrin Repeat Domain Containing Protein 2 (KANK2) Antibody

abx330327-100ul 100 ul
EUR 425
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BPI Fold Containing Family A Member 4, Pseudogene (BPIFA4P) Antibody

abx330328-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Ribosomal Protein L3 Like (RPL3L) Antibody

abx330329-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Transcription Factor A, Mitochondrial (TFAM) Antibody

abx330330-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Tumor Protein P53 Regulated Apoptosis Inducing Protein 1 (TP53AIP1) Antibody

abx330331-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

X-Ray Repair Cross Complementing 3 (XRCC3) Antibody

abx330332-100ul 100 ul
EUR 425
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Serine/Threonine-Protein Kinase ATR (Ab-428) (ATR) Antibody

abx330333-100ul 100 ul
EUR 425
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Lysine Demethylase 4B (KDM4B) Antibody

abx330334-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Myosin Heavy Chain 4 (MYH4) Antibody

abx330335-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Nucleolar pre-ribosomal-associated protein 1 (URB1) Antibody

abx330336-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Endostatin (COL18A1) Antibody

abx330337-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Fibrillin 1 (FBN1) Antibody

abx330338-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Tumor Protein p53 Binding Protein 1 (TP53BP1) Antibody

abx330339-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Alpha Kinase 2 (ALPK2) Antibody

abx330340-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Rho Guanine Nucleotide Exchange Factor 19 (ARHGEF19) Antibody

abx330341-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

ATP Synthase F(0) Complex Subunit C2, Mitochondrial (ATP5G2) Antibody

abx330342-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

BAGE Family Member 2 (BAGE2) Antibody

abx330343-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

BAGE Family Member 3 (BAGE3) Antibody

abx330344-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

B Melanoma Antigen 4 (BAGE4) Antibody

abx330345-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Cyclin Dependent Kinase Like 3 (CDKL3) Antibody

abx330346-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Centromere Protein A (CENPA) Antibody

abx330347-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Cyclin N-Terminal Domain Containing 2 (CNTD2) Antibody

abx330348-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Cystatin 9 Like (CST9L) Antibody

abx330349-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Citrulline (CIT) Antibody

abx330350-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Doublecortin Like Kinase 3 (DCLK3) Antibody

abx330351-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 24 (DDX24) Antibody

abx330352-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

ELOVL Fatty Acid Elongase 3 (ELOVL3) Antibody

abx330353-100ul 100 ul
EUR 425
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Growth Arrest And DNA Damage-Inducible, Gamma Interacting Protein 1 (GADD45GIP1) Antibody

abx330354-100ul 100 ul
EUR 425
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Galactosidase Beta 1 Like 3 (GLB1L3) Antibody

abx330355-100ul 100 ul
EUR 425
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Interleukin 1 Receptor Associated Kinase 1 (IRAK1) Antibody

abx330356-100ul 100 ul
EUR 425
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Mediator Complex Subunit 12 (MED12) Antibody

abx330357-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Mitochondrial Ribosomal Protein L42 (MRPL42) Antibody

abx330358-100ul 100 ul
EUR 425
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Mitochondrial Ribosomal Protein S5 (MRPS5) Antibody

abx330359-100ul 100 ul
EUR 425
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Myomesin 1 (MYOM1) Antibody

abx330360-100ul 100 ul
EUR 425
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NADH Ubiquinone Oxidoreductase Subunit B1 (NDUFB1) Antibody

abx330361-100ul 100 ul
EUR 425
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NADH Ubiquinone Oxidoreductase Subunit V3 (NDUFV3) Antibody

abx330362-100ul 100 ul
EUR 425
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Nephrocystin 4 (NPHP4) Antibody

abx330363-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Pleckstrin Homology Like Domain Family A, Member 2 (PHLDA2) Antibody

abx330364-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Protein Kinase C Theta (PRKCQ) Antibody

abx330365-100ul 100 ul
EUR 425
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Phospholipase A1 member A (PLA1A) Antibody

abx330366-100ul 100 ul
EUR 425
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abx330367-100ul 100 ul
EUR 425
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Plexin Domain Containing 1 (PLXDC1) Antibody

abx330368-100ul 100 ul
EUR 425
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abx330369-100ul 100 ul
EUR 425
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RAB34, Member RAS Oncogene Family (RAB34) Antibody

abx330370-100ul 100 ul
EUR 425
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RAD52 Motif Containing 1 (RDM1) Antibody

abx330371-100ul 100 ul
EUR 425
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EUR 425
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abx330373-100ul 100 ul
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abx330374-100ul 100 ul
EUR 425
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Scavenger Receptor Class F Member 2 (SCARF2) Antibody

abx330375-100ul 100 ul
EUR 425
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SH2 Domain Containing 1B (SH2D1B) Antibody

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abx330383-100ul 100 ul
EUR 425
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abx330384-100ul 100 ul
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abx330385-100ul 100 ul
EUR 425
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abx330386-100ul 100 ul
EUR 425
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Chromodomain Y Like 2 (CDYL2) Antibody

abx330387-100ul 100 ul
EUR 425
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Cyclin E1 (CCNE1) Antibody

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EUR 425
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EUR 425
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EUR 425
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Breast Cancer Type 1 Susceptibility Protein (BRCA1) Antibody

abx330392-100ul 100 ul
EUR 425
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Progesterone Receptor (PGR) Antibody

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EUR 425
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abx330394-100ul 100 ul
EUR 425
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abx330395-100ul 100 ul
EUR 425
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Paxillin (PXN) Antibody

abx330396-100ul 100 ul
EUR 425
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Spleen Associated Tyrosine Kinase (SYK) Antibody

abx330397-100ul 100 ul
EUR 425
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B-Cell Leukemia/Lymphoma 2 (BCL2) Antibody

abx330398-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Receptor tyrosine-protein kinase erbB-2 (ERBB2) Antibody

abx330399-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1) Antibody

abx330400-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Tumor Protein P53 (TP53) Antibody

abx330401-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

H2A Histone Family Member X (H2AFX) Antibody

abx330402-100ul 100 ul
EUR 425
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Cyclin B1 (CCNB1) Antibody

abx330403-100ul 100 ul
EUR 425
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Cell Division Cycle 25C (CDC25C) Antibody

abx330404-100ul 100 ul
EUR 425
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Docking protein 2 (DOK2) Antibody

abx330405-100ul 100 ul
EUR 425
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Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2 (EIF2AK2) Antibody

abx330406-100ul 100 ul
EUR 425
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B-Cell Leukemia/Lymphoma 2 (BCL2) Antibody

abx330407-100ul 100 ul
EUR 425
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Keratin 8 (KRT8) Antibody

abx330408-100ul 100 ul
EUR 425
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Mitogen-activated protein kinase kinase kinase 5 (MAP3K5) Antibody

abx330409-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Heat Shock Transcription Factor 1 (HSF1) Antibody

abx330410-100ul 100 ul
EUR 425
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E3 Ubiquitin-Protein Ligase CBL (CBL) Antibody

abx330411-100ul 100 ul
EUR 425
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Heat Shock 27 kDa Protein 1 (HSPB1) Antibody

abx330412-100ul 100 ul
EUR 425
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Heat Shock 27 kDa Protein 1 (HSPB1) Antibody

abx330413-100ul 100 ul
EUR 425
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Breast Cancer Type 1 Susceptibility Protein (BRCA1) Antibody

abx330414-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1) Antibody

abx330415-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Paxillin (PXN) Antibody

abx330416-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Cyclin Dependent Kinase 4 (CDK4) Antibody

abx330417-100ul 100 ul
EUR 425
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Heat Shock Transcription Factor 1 (HSF1) Antibody

abx330418-100ul 100 ul
EUR 425
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Keratin 18 (KRT18) Antibody

abx330419-100ul 100 ul
EUR 425
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Nibrin (NBN) Antibody

abx330420-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Signal Transducer And Activator Of Transcription 6 (STAT6) Antibody

abx330421-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Signal Transducer And Activator Of Transcription 6 (STAT6) Antibody

abx330422-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Signal Transducer and Activator of Transcription 2 (STAT2) Antibody

abx330423-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Heat Shock 27 kDa Protein 1 (HSPB1) Antibody

abx330424-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Nuclear factor NF-kappa-B p105 subunit (NFKB1) Antibody

abx330425-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Nuclear factor NF-kappa-B p105 subunit (NFKB1) Antibody

abx330426-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

KIT Proto-Oncogene Receptor Tyrosine Kinase (KIT) Antibody

abx330427-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Caveolin 2 (CAV2) Antibody

abx330428-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Tumor Protein P53 (TP53) Antibody

abx330429-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Tumor Protein P53 (TP53) Antibody

abx330430-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Pyruvate Kinase PKM (PKM) Antibody

abx330431-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Tumor Protein P53 (TP53) Antibody

abx330432-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Intercellular Adhesion Molecule 1 (ICAM1) Antibody

abx330433-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Checkpoint Homolog 2 (CHEK2) Antibody

abx330434-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

ZFP42 Zinc Finger Protein (ZFP42) Antibody

abx330435-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Including post-translational modification reactions involving these multivalent proteins can account for the fast dynamics of the ensuing clusters, as is observed via microscopy and photobleaching experiments. The clusters found in simulations also give rise to chromatin domains that conform well with the observation of A/B compartments in HiC experiments.