Rotation Invariant Clustering of 3D Cell Nuclei Shapes.

Cellular imaging with confocal fluorescence laser microscopy gave rise to many new insights into the cellular machinery. One interesting observation suggests that morphology of cell nucleus plays a key role for neutrophilic function, which is an essential part of the innate immune system of most mammals.
Due to the increasing availability of high resolution 3D images coming from the microscope, machine learning becomes a promising tool for automatically discovering underlying hidden structures. Here, the major difficulty consists of selecting an appropriate representation for characterizing the morphology of cell nucleus.
In this work we tackle this problem and propose a fully unsupervised mechanism for finding structure in high-throughput 3D image data. The key component of our approach is based on Generic Fourier Transform (GFT) for 2D images, which for 3D involves spherical coordinate transformation prior to fast Discrete Fourier Transformation.
On top on GFT we apply dimensionality reduction with Principal Component Analysis, followed by generative cluster analysis with a Gaussian Mixture Model. We validate our new approach first on a synthetic 3D-MNIST dataset with random rotations, where quantitative and qualitative results confirm the applicability of the proposed pipeline for exploring shape space in a purely unsupervised manner.

1 KB DNA LADDER, 500UL PER KIT
M-DNA-1KB 1/pk
EUR 70
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COVER GLASS, NO. 1, SQUARE 18 X 18MM
2845-18 100/pk
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2855-18 50/pk
EUR 83
Description: Cover Glass; Cover Glass, CGW

pUC 18 DNA
MSD15 50ug
EUR 122.21

COVER GLASS, NO. 1 1/2, SQUARE 18 X 18MM
2850-18 100/pk
EUR 131
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FT4 (Free thyroxine) ELISA test
18 96T/Box Ask for price
Description: ELISA based test for quantitative detection of FT4 (Free thyroxine)

Encephalitozoon cuniculi whole cell antigen suspension
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EUR 365

Anti-Trimethyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody, Clone#RM175
M06819-18 100ug
EUR 479
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IL-7, Interleukin-7, human
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TSLP, Thymic Stromal Lymphopoietin, human
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AlbuSorb™ Kit
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Syntaxin 18 (Syntaxin 18) Antibody
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Description: AG18 is an inhibitor of EGFR kinase with IC50 values of 35?M. [3]AG18 acts as general tyrosine kinase inhibitor to block tyrosine phosphorylation and events downstream of tyrosine phosphorylation.

AG-18
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Description: AG18 is an inhibitor of EGFR kinase with IC50 values of 35?M. [3]AG18 acts as general tyrosine kinase inhibitor to block tyrosine phosphorylation and events downstream of tyrosine phosphorylation.

AG-18
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Description: AG18 is an inhibitor of EGFR kinase with IC50 values of 35?M. [3]AG18 acts as general tyrosine kinase inhibitor to block tyrosine phosphorylation and events downstream of tyrosine phosphorylation.

AG-18
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PPM-18
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Human cytokeratin 18,CK-18 ELISA Kit
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Human cytokein 18,CK 18 ELISA kit
E01C2328-192T 192 tests
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Human cytokein 18,CK 18 ELISA kit
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Human cytokein 18,CK 18 ELISA kit
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Rat cytokein 18,CK 18 ELISA kit
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Rat cytokein 18,CK 18 ELISA kit
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Rat cytokein 18,CK 18 ELISA kit
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Mouse cytokein 18,CK 18 ELISA kit
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Mouse cytokein 18,CK 18 ELISA kit
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Description: A competitive ELISA for quantitative measurement of Mouse cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse cytokein 18,CK 18 ELISA kit
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Description: A competitive ELISA for quantitative measurement of Mouse cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit cytokein 18,CK 18 ELISA kit
E04C2328-192T 192 tests
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Rabbit cytokein 18,CK 18 ELISA kit
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Rabbit cytokein 18,CK 18 ELISA kit
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Description: A competitive ELISA for quantitative measurement of Rabbit cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Interleukin 18, IL-18 ELISA Kit
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EUR 165
Description: Quantitativesandwich ELISA kit for measuring Mouse Interleukin 18, IL-18 in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Interleukin 18, IL-18 ELISA Kit
1-CSB-E04609m
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
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Description: Quantitativesandwich ELISA kit for measuring Mouse Interleukin 18, IL-18 in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Interleukin 18, IL-18 Elisa Kit
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EUR 165
Description: Quantitativesandwich ELISA kit for measuring Rat Interleukin 18, IL-18 in samples from serum, plasma, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Interleukin 18, IL-18 Elisa Kit
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  • 1 plate of 96 wells
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Description: Quantitativesandwich ELISA kit for measuring Rat Interleukin 18, IL-18 in samples from serum, plasma, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Monkey cytokein 18,CK 18 ELISA kit
E09C2328-192T 192 tests
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Monkey cytokein 18,CK 18 ELISA kit
E09C2328-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey cytokein 18,CK 18 ELISA kit
E09C2328-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human cytokeratin 18, CK-18 ELISA Kit
CSB-E09172h-24T 1 plate of 24 wells
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Description: Quantitativesandwich ELISA kit for measuring Human cytokeratin 18, CK-18 in samples from serum, plasma, tissue homogenates, cell lysates, cell culturesupernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human cytokeratin 18, CK-18 ELISA Kit
1-CSB-E09172h
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human cytokeratin 18, CK-18 in samples from serum, plasma, tissue homogenates, cell lysates, cell culturesupernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Dog Interleukin 18, IL-18 ELISA KIT
CSB-E09848c-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Dog Interleukin 18, IL-18 in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Then we apply our proposed technique to a new collected dataset of high resolution 3D images of neutrophile nuclei suggesting a clustering model with six significant clusters of morphological cell nuclei prototypes. We visualize differences in the cell shape clusters by providing prototypical examples of neutrophilic cell nuclei.