Rotation Invariant Clustering of 3D Cell Nuclei Shapes.

Cellular imaging with confocal fluorescence laser microscopy gave rise to many new insights into the cellular machinery. One interesting observation suggests that morphology of cell nucleus plays a key role for neutrophilic function, which is an essential part of the innate immune system of most mammals.
Due to the increasing availability of high resolution 3D images coming from the microscope, machine learning becomes a promising tool for automatically discovering underlying hidden structures. Here, the major difficulty consists of selecting an appropriate representation for characterizing the morphology of cell nucleus.
In this work we tackle this problem and propose a fully unsupervised mechanism for finding structure in high-throughput 3D image data. The key component of our approach is based on Generic Fourier Transform (GFT) for 2D images, which for 3D involves spherical coordinate transformation prior to fast Discrete Fourier Transformation.
On top on GFT we apply dimensionality reduction with Principal Component Analysis, followed by generative cluster analysis with a Gaussian Mixture Model. We validate our new approach first on a synthetic 3D-MNIST dataset with random rotations, where quantitative and qualitative results confirm the applicability of the proposed pipeline for exploring shape space in a purely unsupervised manner.

1 KB DNA LADDER, 500UL PER KIT

M-DNA-1KB 1/pk
EUR 70
Description: Bioscience Mol Bio; DNA Ladder

COVER GLASS, NO. 1, SQUARE 18 X 18MM

2845-18 100/pk
EUR 112
Description: Cover Glass; Cover Glass, CGW

COVER GLASS, NO. 2, SQUARE 18 X 18MM

2855-18 50/pk
EUR 83
Description: Cover Glass; Cover Glass, CGW

pUC 18 DNA

MSD15 50ug
EUR 122.21

COVER GLASS, NO. 1 1/2, SQUARE 18 X 18MM

2850-18 100/pk
EUR 131
Description: Cover Glass; Cover Glass, CGW

FT4 (Free thyroxine) ELISA test

18 96T/Box Ask for price
Description: ELISA based test for quantitative detection of FT4 (Free thyroxine)

Encephalitozoon cuniculi whole cell antigen suspension

18-2002 1 ml
EUR 365

Anti-Trimethyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody, Clone#RM175

M06819-18 100ug
EUR 479
Description: Anti-Trimethyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody, Clone#RM175 tested in WB, ELISA, Multiplex, IHC, reactive to All Vertebrates

IL-7, Interleukin-7, human

RC212-18 2ug
EUR 104.38

TSLP, Thymic Stromal Lymphopoietin, human

RC213-18 2ug
EUR 104.38

LIF, Leukemia inhibitory factor, human

RC214-18 2ug
EUR 101.33

FGF-7, KGF-1, Fibroblast Growth Factor-7, human

RC215-18 2ug
EUR 104.38

Epiregulin, human

RC216-18 5ug
EUR 104.38

IFN lambda 1 (IL-29), human

RC217-18 5ug
EUR 104.38

GMF beta, Glia Maturation Factor beta, human

RC218-18 2ug
EUR 104.38

BMP-7, Bone Morphogenetic Protein-7, human

RC219-18 2ug
EUR 104.38

IL-7, Interleukin-7, murine (mouse)

RC232-18 2ug
EUR 104.38

LIF, Leukemia inhibitory factor, murine (mouse)

RC234-18 5ug
EUR 104.38

FGF-7, Fibroblast Growth Factor-7, murine (mouse)

RC235-18 2ug
EUR 104.38

GMF beta, Glia Maturation Factor beta, murine (mouse)

RC238-18 2ug
EUR 104.38

IL-7, Interleukin-7, rat

RC252-18 2ug
EUR 104.38

VEGF165, rat

RC256-18 1mg
EUR 2364.2

GMF beta, rat

RC258-18 2ug
EUR 101.33

IFN-tau, Interferon-tau, ovine

RC277-18 2ug
EUR 104.38

NAP-2, CXCL7, human

RC312-18 2ug
EUR 104.38

MCP-3, CCL7, human

RC315-18 2ug
EUR 104.38

MCP-3, CCL7, murine (mouse)

RC335-18 2ug
EUR 104.38

NAP-2, CXCL7, rat

RC352-18 2ug
EUR 104.38

MCP-3, CCL7, rat

RC355-18 2ug
EUR 104.38

UBC7, Ubiquitin Conjugating Enzyme 7 (His6-tagged), human

RC612-18 50ug
EUR 169.63

Sparc, human

RC712-18 50ug
EUR 152.66

AlbuSorb™ Kit

A185-18 18 grams AlbuSorb™ Bead & Buffer (360 preps, 25 µl serum) Ask for price
Description: Albumin Removal Kit

Syntaxin 18 (Syntaxin 18) Antibody

20-abx115967
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Syntaxin 18 (Syntaxin 18) Antibody

abx238449-100ug 100 ug
EUR 509

Interleukin 18 (IL-18) Antibody

20-abx225240
  • EUR 370.00
  • EUR 606.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 50 ul

Mouse cytokeratin 18(CK-18)

QY-E21751 96T
EUR 374

Cytokeratin 18 / CK-18 (KRT18) Antibody

abx413457-5ml 5 ml
EUR 606

Cytokeratin 18 / CK-18 (KRT18) Antibody

abx413458-1ml 1 ml
EUR 342

Mouse Interleukin-18 (IL-18) Antibody

30119-05111 150 ug
EUR 261

Human Interleukin-18 (IL-18) Antibody

32199-05111 150 ug
EUR 261

18-Hydroxycamptothecin

TBZ1416 unit Ask for price

NOC-18

2492-10
EUR 169

NOC-18

2492-50
EUR 479

AP-18

20-abx076607
  • EUR 300.00
  • EUR 718.00
  • 10 mg
  • 50 mg

ML-18

HY-101844 10mM/1mL
EUR 310

RN-18

HY-102014 100mg
EUR 1345

18-Hydroxycorticosterone

HY-W013179 1mg
EUR 2116

AG-18

A1173-100 100 mg
EUR 490
Description: AG18 is an inhibitor of EGFR kinase with IC50 values of 35?M. [3]AG18 acts as general tyrosine kinase inhibitor to block tyrosine phosphorylation and events downstream of tyrosine phosphorylation.

AG-18

A1173-25 25 mg
EUR 189
Description: AG18 is an inhibitor of EGFR kinase with IC50 values of 35?M. [3]AG18 acts as general tyrosine kinase inhibitor to block tyrosine phosphorylation and events downstream of tyrosine phosphorylation.

AG-18

A1173-5 5 mg
EUR 108
Description: AG18 is an inhibitor of EGFR kinase with IC50 values of 35?M. [3]AG18 acts as general tyrosine kinase inhibitor to block tyrosine phosphorylation and events downstream of tyrosine phosphorylation.

AG-18

A1173-5.1 10 mM (in 1mL DMSO)
EUR 113
Description: AG18 is an inhibitor of EGFR kinase with IC50 values of 35?M. [3]AG18 acts as general tyrosine kinase inhibitor to block tyrosine phosphorylation and events downstream of tyrosine phosphorylation.

AP 18

B7349-10 10 mg
EUR 144
Description: AP-18 is a selective channel blocker which can reversibly inhibit TRPA1 of human and mouse with IC50 of 3.1 µM and 4.5 µM, respectively.

AP 18

B7349-25 25 mg
EUR 270
Description: AP-18 is a selective channel blocker which can reversibly inhibit TRPA1 of human and mouse with IC50 of 3.1 µM and 4.5 µM, respectively.

AP 18

B7349-5 5 mg
EUR 112
Description: AP-18 is a selective channel blocker which can reversibly inhibit TRPA1 of human and mouse with IC50 of 3.1 µM and 4.5 µM, respectively.

AP 18

B7349-50 50 mg
EUR 425
Description: AP-18 is a selective channel blocker which can reversibly inhibit TRPA1 of human and mouse with IC50 of 3.1 µM and 4.5 µM, respectively.

PPM-18

C4074-10 10 mg
EUR 192
Description: PPM-18 is a chemically synthesized naphthoquinone derivative and an anti-inflammatory agent that inhibits the expression of inducible NO synthase (iNOS). NOS catalyzes the oxidation of the amino acid L-arginine to form NO.

PPM-18

C4074-25 25 mg
EUR 363
Description: PPM-18 is a chemically synthesized naphthoquinone derivative and an anti-inflammatory agent that inhibits the expression of inducible NO synthase (iNOS). NOS catalyzes the oxidation of the amino acid L-arginine to form NO.

PPM-18

C4074-5 5 mg
EUR 129
Description: PPM-18 is a chemically synthesized naphthoquinone derivative and an anti-inflammatory agent that inhibits the expression of inducible NO synthase (iNOS). NOS catalyzes the oxidation of the amino acid L-arginine to form NO.

Canine Interleukin-18, IL-18 ELISA Kit

ELA-E0064d 96 Tests
EUR 928

Mouse Interleukin-18, IL-18 ELISA Kit

ELA-E0064m 96 Tests
EUR 865

Chicken Interleukin 18,IL-18 ELISA KIT

CN-00786C1 96T
EUR 434

Chicken Interleukin 18,IL-18 ELISA KIT

CN-00786C2 48T
EUR 284

Canine Interleukin 18,IL-18 ELISA KIT

CN-00930C1 96T
EUR 465

Canine Interleukin 18,IL-18 ELISA KIT

CN-00930C2 48T
EUR 315

PoFAine Interleukin 18,IL-18 ELISA Kit

CN-01257P1 96T
EUR 458

PoFAine Interleukin 18,IL-18 ELISA Kit

CN-01257P2 48T
EUR 307

Rat Interleukin 18,IL-18 Elisa Kit

CN-01601R1 96T
EUR 455

Rat Interleukin 18,IL-18 Elisa Kit

CN-01601R2 48T
EUR 304

Mouse Interleukin 18,IL-18 ELISA Kit

CN-02452M1 96T
EUR 447

Mouse Interleukin 18,IL-18 ELISA Kit

CN-02452M2 48T
EUR 296

Human Interleukin 18,IL-18 ELISA KIT

CN-03294H1 96T
EUR 434

Human Interleukin 18,IL-18 ELISA KIT

CN-03294H2 48T
EUR 284

Human cytokeratin 18,CK-18 ELISA Kit

CN-04602H1 96T
EUR 464

Human cytokeratin 18,CK-18 ELISA Kit

CN-04602H2 48T
EUR 313

Human cytokein 18,CK 18 ELISA kit

E01C2328-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Human cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human cytokein 18,CK 18 ELISA kit

E01C2328-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Human cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human cytokein 18,CK 18 ELISA kit

E01C2328-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat cytokein 18,CK 18 ELISA kit

E02C2328-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat cytokein 18,CK 18 ELISA kit

E02C2328-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat cytokein 18,CK 18 ELISA kit

E02C2328-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse cytokein 18,CK 18 ELISA kit

E03C2328-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse cytokein 18,CK 18 ELISA kit

E03C2328-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse cytokein 18,CK 18 ELISA kit

E03C2328-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit cytokein 18,CK 18 ELISA kit

E04C2328-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit cytokein 18,CK 18 ELISA kit

E04C2328-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit cytokein 18,CK 18 ELISA kit

E04C2328-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Interleukin 18, IL-18 ELISA Kit

CSB-E04609m-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Mouse Interleukin 18, IL-18 in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Interleukin 18, IL-18 ELISA Kit

1-CSB-E04609m
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Interleukin 18, IL-18 in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Interleukin 18, IL-18 Elisa Kit

CSB-E04610r-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Rat Interleukin 18, IL-18 in samples from serum, plasma, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Interleukin 18, IL-18 Elisa Kit

1-CSB-E04610r
  • EUR 603.00
  • EUR 4247.00
  • EUR 2260.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Interleukin 18, IL-18 in samples from serum, plasma, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Monkey cytokein 18,CK 18 ELISA kit

E09C2328-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey cytokein 18,CK 18 ELISA kit

E09C2328-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey cytokein 18,CK 18 ELISA kit

E09C2328-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey cytokein 18,CK 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human cytokeratin 18, CK-18 ELISA Kit

CSB-E09172h-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human cytokeratin 18, CK-18 in samples from serum, plasma, tissue homogenates, cell lysates, cell culturesupernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human cytokeratin 18, CK-18 ELISA Kit

1-CSB-E09172h
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human cytokeratin 18, CK-18 in samples from serum, plasma, tissue homogenates, cell lysates, cell culturesupernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Dog Interleukin 18, IL-18 ELISA KIT

CSB-E09848c-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Dog Interleukin 18, IL-18 in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Then we apply our proposed technique to a new collected dataset of high resolution 3D images of neutrophile nuclei suggesting a clustering model with six significant clusters of morphological cell nuclei prototypes. We visualize differences in the cell shape clusters by providing prototypical examples of neutrophilic cell nuclei.